Melatonin Timing Calculator
Determine the optimal time and dosage for taking melatonin supplements based on your specific needs and circumstances.
Melatonin Dosage & Timing Guidelines
General guidelines for melatonin supplementation based on indication:
Indication |
Recommended Dosage |
Timing Considerations |
Trouble falling asleep |
0.3-5 mg |
Take 1 hour before bedtime |
Jetlag, eastbound |
0.5-5 mg |
Take 2 days before flight at 7 PM, continue for 4 days after arrival before bedtime |
Jetlag, westbound |
0.5-5 mg |
Take for 4 days after arrival before bedtime |
Insomnia in blind people |
0.5 mg |
Take around 9-10 PM before going to sleep |
Beta-blockers insomnia |
2.5 mg |
Take daily for up to 4 weeks |
Endometriosis |
10 mg |
Take daily for up to 8 weeks |
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Reduce Light Exposure
Avoid bright lights and screens 1-2 hours before taking melatonin for optimal effectiveness.
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Start Low
Begin with the lowest effective dose and increase gradually as needed after consulting a healthcare provider.
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Consistent Timing
Take melatonin at the same time each night to help regulate your body’s circadian rhythm.
Important Melatonin Facts
- Melatonin is a hormone naturally produced by the pineal gland that helps regulate sleep-wake cycles.
- Blood levels of melatonin rise 1-5 times above physiological peak about an hour after taking 0.1-0.5 mg doses.
- Higher doses (1-5 mg) can elevate blood levels 10-100 times above normal nighttime peak levels.
- Melatonin levels typically return to baseline 4-8 hours after supplementation.
- The most common side effects of melatonin supplementation include headaches, dizziness, nausea, and drowsiness.
- Natural melatonin production decreases with age, which is why older adults may benefit from supplementation.
- Melatonin supplements are available over-the-counter in the US but are prescription-only in many other countries.
- Some medications, including beta-blockers, can interfere with natural melatonin production.
- Melatonin should be used with caution by those who are pregnant, breastfeeding, or have autoimmune disorders.
- The long-term effects of regular melatonin supplementation are still not fully understood.
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Factors Affecting Melatonin Effectiveness
Factor |
Description |
Light Exposure |
Blue light from screens can suppress natural melatonin production. Avoid screens and bright lights 1-2 hours before bed. |
Timing |
Taking melatonin at the wrong time can disrupt your circadian rhythm rather than help it. |
Dosage |
More isn’t always better. Sometimes lower doses (0.3-0.5 mg) are more effective than higher doses. |
Food Interactions |
Taking melatonin with food, especially high-fat meals, may delay its absorption and effect. |
Individual Metabolism |
Liver function and individual metabolism can affect how quickly melatonin is processed in your body. |
Age |
Children, adults, and seniors may require different dosages for optimal effectiveness. |
Caffeine & Alcohol |
Both can interfere with melatonin’s effectiveness and should be avoided close to bedtime. |
Medication Interactions |
Melatonin can interact with blood thinners, immunosuppressants, diabetes medications, and birth control pills. |
Supplement Quality |
The FDA doesn’t regulate melatonin supplements, so quality and actual content can vary between brands. |
Health Conditions |
Certain health conditions like depression, dementia, and seizure disorders may affect how melatonin works in your body. |
Age-Specific Melatonin Recommendations
Age Group |
Generally Effective Dosage Range |
Special Considerations |
Children |
0.1 to 3 mg |
Should only be used under healthcare provider supervision. May be helpful for certain sleep disorders. |
Adolescents |
3 to 12 mg |
May experience more delayed sleep phase disorders. Should discuss with healthcare providers. |
Adults |
1 to 25 mg |
Start with the lowest effective dose (0.5-3 mg) and increase as needed. Most adults don’t need high doses. |
Older Adults |
1 to 6 mg |
May be more sensitive to side effects. Natural melatonin production decreases with age. |